We assessed the relevance of identified menarche loci to other traits by comparing SNPs significantly associated with age at menarche with published GWAS findings or by using publicly available data from the Genetic Investigation of Anthropometric Traits (GIANT) consortium22,21 and the GEnetic Factors for OS (GEFOS) consortium27. In addition, we requested look-ups up the 123 menarche SNPs for association with puberty timing assessed by Tanner staging in the Early Growth Genetics (EGG) consortium77.
