In HS we observed association of potential eQTL rs3765598 with SLE. This SNP is in a potential enhancer of regulatory chromatin site for CD4+CD25−CD45RO+ memory primary cells. Although the minor allele for rs3765598 is less common in Yorubans (MAF = 4%), and is more common in individuals of European descent (CEU MAF = 23%), it was not associated in our EA population (P = 0.75).