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Chunk #67 — Discussion — Implications and Conclusions

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Behavioral disinhibition: liability for externalizing spectrum disorders and its genetic and environmental relation to response inhibition across adolescence.
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response inhibition as an endophenotype will depend in large part on how it is measured. In particular, using individual tasks is unlikely to be fruitful. As the factor loadings for the tasks demonstrate, although the latent response inhibition factor is almost entirely heritable, the individual measures are quite impure, with only a small portion of their variances tapping the latent factor. Thus, future studies would benefit from incorporating multiple measures of inhibition and using either latent variable analysis or aggregation to arrive at a purer measure of response inhibition abilities (Miyake, Emerson, & Friedman, 2000).