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Chunk #44 — 4.0. Discussion

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Cholinergic receptor gene (CHRM2) variation and familial loading for alcohol dependence predict childhood developmental trajectories of P300.
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The present results based on auditory P300 are in accord with two previous studies from our laboratory involving multiple measures of visual P300 in finding predictable age related effects (Hill et al 1999; Hill and Shen, 2002) and confirm age- related visual P300 findings obtained with up to three repeated assessments from the Minnesota group (Carlson and Iacono, 2006; Iacono and Malone, 2011).