As of 1st March 2013, we have almost 1500 networks that collectively contain nearly 300 million interactions covering almost 150 000 genes. All of this data are also available for download from the GeneMANIA data archive (http://pages.genemania.org/data/)—also new since 2010. This site stores current and previous data versions (networks and identifiers) in simple text formats in addition to a ‘precombined’ network that integrates multiple individual GeneMANIA networks into a single large network. This ‘precombined’ network can be used like other published functional interaction networks [recent examples include (8–10)], but the link (i.e., interaction) weights have a slightly different meaning (see below). Currently this precombined network consists of the set of default networks, combined using the GO-based Biological Process method (see Table 1).
