Transposon insertions cause partial loss of function in Drosophila Clic(A) The Clic locus and transposon insertions. Transcription of Clic is from left to right. The Clic transcription unit is represented by the filled rectangle with nucleotide positions indicated above (coordinates from FlyBase annotation release 5.33). Exons are represented by rectangles below the transcription unit with protein coding sequences and untranslated regions depicted as grey and open rectangles, respectively. Introns are represented as a line and transposons as triangles. Scale bar (upper right) is 1000 bp. Schematic adapted from FlyBase. (B) Whole-body Clic mRNA expression in transposon lines. Expression of Clic mRNA in flies heterozygous for the G0472 and the EY04209 transposons was reduced relative to w1118 controls.
