Chunk #29 — Discussion

Source: Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation.
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In this study, we tested the regulation of brain FoxO1 and FoxO3a by serotonin and imipramine, and the behavioral manifestations of genetic insufficiency of each. We focused on FoxO1 and FoxO3a because they are abundant in the adult brain (62-64).