Trait-related vulnerability to elevated externalizing problems as well as reduced cognition have been speculated to contribute to vulnerability to stage-based addiction transitions (26). We used the full scale IQ estimation generated from the National Institutes of Health Toolbox Cognitive Battery (27) and externalizing problems as assessed on The Child Behavior Checklist (CBCL) (28) to test whether alcohol involvement PRS and related brain structure correlates are associated with variability in cognition and externalizing.
