Chunk #21 — Discussion

Source

PRSice-2: Polygenic Risk Score software for biobank-scale data.

Embedded

yes

Text

PRSice-2 implements a standard approach for performing PRS analyses. For PRS analyses performed in family data or across diverse populations, for instance, results should be interpreted carefully [14] and extensions of the standard PRS approach or alternatives may be required [14,28–30] to generate more informative results.