Because developmental trajectories of P300 have been shown to differ by familial risk group status (Hill et al., 1999) and are related to the presence of child/adolescent psychiatric status (Hill and Shen, 2002), it was of interest to determine if variation in developmental trajectories of P300 obtained from repeated assessments would be related to variation in the CHRM2 gene, a gene that has been shown to be associated with both AD risk and cross-sectionally obtained P300 variation.
