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Chunk #8 — Method — Screening and Experimental Procedures

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Subjective response to alcohol among alcohol-dependent individuals: effects of the μ-opioid receptor (OPRM1) gene and alcoholism severity.
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Participants completed two randomized infusion sessions; one alcohol infusion and one saline control infusion. Alcohol administration was conducted using a single-blinded, randomized, counterbalanced, crossover design. Infusion sessions were separated by 1–2 weeks, with the observed time between infusions being 10.6 days. Participants were invited for an individual session of motivational interviewingupon completion of the study (34/43 completed the MI).