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Chunk #35 — DISCUSSION

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Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study.
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SNPs associated with multiple distinct phenotypes might be more central to the functioning of the gene. As an illustration, we looked up this rs1271459. No information was available for this SNP itself, but its proxy rs9820373 is a significant eQTL for CADM2 expression in the subcutaneous adipose tissue (p fdr = 5.4E‐4). 55 This is interesting as CADM2 has been associated with BMI, 56 potentially through impulsive over‐eating.