Table 6 summarizes mean AUC estimates and median p-values for each set of SNPs meeting p-value thresholds across the 100 random divisions of the SAGE-COGA combined sample. AUC estimates were significant at p < 0.05 for subsets of SNPs meeting p-value thresholds of 0.01 and greater. Figure 3 illustrates the AUC estimates of genetic sum scores created based on varying p-value thresholds. Although the p-value threshold at which AUC value peaked varied across subsets, AUC point estimates showed an increasing trend across the subsets as the p-value threshold used for SNP selection became less stringent.
