Chunk #21 — Methods

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Investigating causality in associations between smoking initiation and schizophrenia using Mendelian randomization.

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Single nucleotide polymorphisms (SNPs) associated with smoking initiation, and schizophrenia risk, were identified from genomewide significant hits in the Tobacco And Genetics (TAG) consortium13 and the Psychiatric Genetics Consortium (PGC2)12 GWAS, respectively.