In both Phase 1 analyses, we identified population-specific variants and variants associated with risk in both EAs and AAs and (Figures S2 and S3 in Supplement 1]), including GWS associations in AAs with PITPNM3 (rs9913974, p=8.4×10−9) for the case-control model and KCNC1 (rs60349741, p=1.3×10−8) and HHLA2 (rs73204138, p=3.7×10−8) for the Sympcountadj model. The p-values for these findings are negligibly inflated (Figures S4 and S5 in Supplement 1]) and the SNPs were well imputed (Table S1 in Supplement 1]). We also identified a possible association with a DISC1 polymorphism (rs2738888, AA p=8.47×10−4; EA p=1.74×10−3; meta p=5.22×10−6 (discussed below)).
