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Chunk #20 — BACKGROUND — First findings of ENIGMA‐OCD: Cortical thickness, surface area and subcortical volume

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An overview of the first 5 years of the ENIGMA obsessive-compulsive disorder working group: The power of worldwide collaboration.
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findings fit well with all prior meta‐ and mega‐analyses (De Wit et al., 2014; Peng et al., 2012; Radua et al., 2010; Radua & Mataix‐Cols, 2009; Rotge et al., 2010) and appear to be more specific to OCD. Larger pallidum could be due to chronic compulsivity (Van den Heuvel et al., 2016). At the same time, since larger pallidum has also been reported in schizophrenia (Van Erp et al., 2016), use of antipsychotic medication might partly explain the findings. Indeed, in our analysis by age‐group and medication class (Ivanov et al., 2019), a larger pallidum was seen particularly in adolescent and adult patients taking antipsychotics.