Chunk #6 — Results — Local genetic effects on blood gene expression

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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.

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We identified cis-eQTLs (SNP gene distance <1 Mb, FDR<0.05; Methods) for 16,987 genes (88.2% of the 19,250 autosomal genes expressed in blood and tested in the cis-eQTL analysis; Figure 1b).