We conducted a comprehensive review of the literature on biological pathways that have been hypothesized to influence risk tolerance. The 132 articles identified by review are compiled in Supplementary Table 1. The Supplementary Note and Supplementary Tables 15, 16, and 33–34 provide further details and report the results of the various analyses we conducted to assess whether the pathways and genes that have previously been hypothesized to relate to risk tolerance do indeed show evidence of association with risk tolerance.
