Behavioral tests were scored using either ANY-maze (Stoelting, Wood Dale, IL) or EthoVision (Noldus). Behavioral testing began at either 25 weeks (for pre-pulse inhibition) or 30–36 weeks (all other tests), and typically lasted 3 weeks; starting age was matched between experimentals and controls. A total of 6–12 recipient mice were engrafted and tested per cell line, or 17–36 mice per group for each behavioral comparison, with a roughly equal balance of male (M) and female (F) recipients. All behavioral tests were done by experimenters blinded as to the treatment condition and implanted cell line.
