Transcriptomic Imputation was carried out individually for each case-control PGC-SCZ cohort with available dosage data (44/52 cohorts). Predicted gene expression levels were computed using the DLPFC predictors described in this manuscript, as well as for 11 other brain tissues prediction databases created using GTEx tissues15,21,81,82 (Figure 1c). Associations between predicted gene expression values and case-control status were calculated using a linear regression test in R. Ten ancestry principal components were included as covariates. Association tests were carried out independently for each cohort, across 12 brain tissues.
