Chunk #53 — Online Methods (Limit 3,000 words, at end of manuscript, currently 2,064) — Transcriptomic Imputation and association testing

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Gene expression imputation across multiple brain regions provides insights into schizophrenia risk.

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yes

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For the eight PGC cohorts with no available dosage data, the three PGC trio-based analyses, and the CLOZUK2 cohort, a summary-statistic based transcriptomic imputation approach was used (“S-PrediXcan25”), as described previously.