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Chunk #11 — Results

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The mu-opioid receptor gene and smoking initiation and nicotine dependence.
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Table 2 summarized the results of allelic and genotypic association analyses. Three SNPs (rs2075572, rs10485057 and rs10485058) showed significant differences (P = 0.036, 0.012 and 0.033, respectively) in genotype frequencies between the non-smokers and regular smokers. One SNP (rs2075572) showed significant difference in allele frequency between the non-smokers and regular smokers (P = 0.016). For ND, only one SNP (rs10485057) reached nominal significance (P = 0.0297). The non-synonymous marker, rs1799971, was not significant for SI or ND.