Table 2 lists all SNPs that yielded P-values < 10−5 with either phenotype. The results are ordered by significance of P-values for the primary phenotype of natural log-transformed CD symptom count, although the SNPs listed under the horizontal rule in the table are included for P<10−5 with the CD case status. The left portion of the table reports results for the natural log-transformed CD symptom count, and the corresponding results for CD case status are included in the right portion of the table. All SNPs that met criteria for P < 10−5 for one of the phenotypes also showed a corresponding P-value < 0.01 with the other phenotype, indicating general consistency across the results for both the quantitative CD symptom count variable and CD case status. Figure 1 shows a q–q plot for the observed versus expected distribution of P-values for the primary CD symptom count analysis. Four SNPs reached genome-wide significance with CD symptom count, based on P < 5 × 10−8. Two of these SNPs (rs16891867 and rs1861046) were in the gene C1QTNF7 (C1q and tumor necrosis factor-related
