Our participating groups contributed a total of 43 165 total subjects genotyped for 5-HTTLPR and assessed for depression and childhood maltreatment and/or other stressful life events. Of these, 40 693 (94.3%) were of European ancestry, and after harmonization 38 802 subjects contributed to at least one analysis. The non-European samples were distributed across five strata (African, African-European Admixed, Asian, Pacific Islander, and Hispanic) and were not meta-analyzed due to small sample size. Supplemental Table S5 provides key demographic information about the data included in the meta-analyses (e.g., N, S allele frequency, frequencies of the key phenotypes). For each of the datasets in Table S5, Table S6 lists whether the study design was cross-sectional or longitudinal, the criteria used to diagnose depression, and the assessments used to determine childhood maltreatment and other stressful life events. Table S7 provides information about additional datasets for which the script was run, but whose results could not be included in any of the primary or secondary analyses. Further details about each participating study can be found in Supplemental Table S8.
