paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #12 — 2. Results — 2.2 Phase locking in response to ethanol in rats and humans

Source
Ethanol reduces the phase locking of neural activity in human and rodent brain.
Embedded
yes

Text

in the delta (F=8.26, df=1,37, p<0.007), theta (F=10.84, df=1,37, p<0.002), and alpha (F=11.89, df=1,37, p<0.001) frequency ranges. Grand averages of the PLI values for the entire group of subjects (n = 38) for the ethanol and placebo condition are presented in Figure 2. Figure 3a gives the mean (± SE) values for the PLI for each frequency range for the three electrode locations for the ethanol and placebo condition, for the infrequent/target tone in the human participants. The phase difference lock index (PDLI) for the electrode pair FZ and PZ, for ethanol and placebo condition is shown in Figure 4a. Reductions in PDLI at 60 minutes following ethanol as compared to placebo were found in the delta (F=5.99, df=1,37, p<0.019) and theta (F=4.6, df=1,37, p<0.038) frequency ranges. No significant differences were seen for the electrode pairs FZ and CZ, or CZ and PZ, most likely because the leads were closer together.