case–control GWAS sample similarly showed evidence for an obesity association signal. The maximal pairwise correlation coefficient between each of these two CNV markers associated with obesity ranged from 0.24 to 0.91 as estimated in the parents, whereas the range of pairwise correlations between those two markers with minimal P-values in the family-based and in the case–control GWAS discovery sample was 0.15–0.84. Among the 20 CNVRs associated with obesity, reduced copy numbers (deletions) were associated with obesity in 18 CNVRs (Table 2).
