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Chunk #8 — Materials and Methods — Sample

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The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity.
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The subsample of participants included in analyses of the externalizing phenotype consisted of 531 white non-Hispanic veterans and their intimate partners (60.3% male) with a mean age of 51.68 years (range: 21–75). Participants were included in this analysis whether or not they had experienced a trauma. The subsample of participants included in analyses of lifetime PTSD diagnosis were 491 white non-Hispanic veterans and their intimate partners (65% men, mean age: 51.93, range: 21–75), all of whom had been exposed to a DSM-IV defined PTSD Criterion A traumatic event (n=295 cases and n=196 controls). The vast majority of the participants (90.7%) were included in both subsamples.