Sample ascertainment, characterization, genotyping, and data cleaning methods have been described elsewhere in detail (Logue et al., 2012) and diagrammed in Supplementary Figure 1. Briefly, we examined a subset of a cohort of military veterans and their intimate partners ascertained from two studies performed at U.S. Department of Veterans Affairs (VA) medical centers. Both studies were reviewed and approved by the appropriate institutional review boards. In this study, we focused on the subset of this cohort determined to be of white non-Hispanic ancestry (n=554) based on STRUCTURE (Falush et al., 2003; Pritchard et al., 2000) analysis. Within these study participants, there were 339 males and 215 females. There were 334 participants in couple pairs (60%, 167 couples). In this sample, 15 PTSD cases met criteria for a bipolar 1 diagnosis and two met for a bipolar 2 diagnosis. The presence of schizophrenia was not assessed.
