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Chunk #26 — DISCUSSION

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Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
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Variants in DLEU7 have also been associated with height in three GWASs (27–29), although the LD between the topmost SNPs from these studies and the topmost SNP from the present study is low (r2 < 0.01), suggesting that the underlying signals are independent of each other. Transcription factors of DLEU7 are known to have roles in cell proliferation and differentiation (30).