After conditioning on the top-SNP (rs56113850), rs113288603 emerged as the second independent SNP. As this SNP showed no association in either the cohort-specific GWAS or in meta-analysis, we further scrutinized the plausible interplay between rs56113850 and rs113288603 within the largest of our cohorts (YFS), by testing how adding the other SNP or an interaction term (rs56113850*rs113288603) to the model affects the effect sizes.
