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Chunk #50 — Discussion

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Regional Differences and Similarities in the Brain Transcriptome for Mice Selected for Ethanol Preference From HS-CC Founders.
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encodes TrkB, a receptor for Bdnf, moves from non-hub status in the Low selected line to hub status in the High line. Numerous studies have linked the regulation of ethanol consumption to the regulation of Bdnf function; Darcq et al. (2016) have found in the rat dorsolateral striatum the Bdnf-TrkB system is essential to maintaining moderate ethanol intake. Our data suggest that manipulating this system in the CeA will likely have marked effects on ethanol preference.