We tested effects of PPAR agonists on ethanol consumption and preference in continuous 2BC drinking in male C57BL/6J mice. Figure 1 (left panel) shows the total ethanol consumption over 24 hours averaged for days 5 and 6. Feno and tesa decreased ethanol consumption by approximately 50% and 75%, respectively, while beza had no statistically significant effect (Figure 1). Ethanol preference followed the same pattern as ethanol consumption, and none of the treatments altered total fluid intake (Figure 1).
