to initiating alcohol use) is associated with activation patterns different than controls in brain regions that are part of the executive control and appetitive drive network. Recent work has examined resting state fMRI synchrony in multiple brain networks in individuals with current AUDs (Weiland et al., 2014). The fMRI time series measures of synchrony (i.e., average within network correlations of BOLD signal magnitude across the network's nodes) were computed for 14 networks in each of 422 individuals with active AUDs and 97 controls. Network strength on average for all networks (multivariate test) was lower for AUD than controls. Univariate tests showed lower synchrony in AUD vs. controls for the left executive control network, sensorimotor, basal ganglia, and primary visual networks.
