neuronal migration. 60 A prior study also reported associations between an intergenic locus near SETBP1 and externalising behaviour that was further substantiated by gene‐based tests providing additional support for the novel result reported here. 54 Other genes showed more specific tissue and cell‐type associations. For example, BRSK2 (rs61869029), which encodes a protein involved in neuron polarisation and axonogenesis and has been previously implicated in risk taking, 22 and CDH2 (rs4239453), which encodes a protein involved in cell‐to‐cell adhesion, both showed DA‐midbrain specificity in H‐MAGMA analyses.
