paperKB
coga / coga-kb
Help
Sign in

Chunk #10 — Materials and Methods — Genotyping

Source
Gamma-aminobutyric acid system genes--no evidence for a role in alcohol use and abuse in a community-based sample.
Embedded
yes

Text

in which only paternally-transmitted copies of the genes are expressed (Meguro et al., 1997), markers on these genes would be inappropriate to assess using methods that do not account for the identity of the parent from whom each allele was transmitted, and were therefore excluded from analyses. All available SNPs on the Illumina 660w Quad array within the designated boundaries of each GABA-related gene that passed preliminary quality control procedures were included in subsequent analyses. In all, 737 SNP markers in or near 31 genes (including 17 GABA receptor subunit genes) were retained (Table 2.).