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Chunk #20 — Discussion

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Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver.
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Our study was performed in the human liver with a focus on ADME genes, which have not been given special attention in previous studies. It replicates a former study by Schadt et al.16 (the Seattle study) in terms of general approach and tissue analyzed, and we therefore strived to compare the results of the two studies in detail.