In this study, we examined all 29 genes encoding known subunits of the SWI/SNF chromatin remodeling complex in humans for association with AD in the COGA adult case-control sample (Bierut et al., 2002) and with antisocial behavior in the younger S4S sample (Dick et al., 2014). We further hypothesized that we would find evidence for replication of association of SWI/SNF genes at the level of the biological complex, rather than at the level of individual SNPs or genes, which may vary from sample to sample.
