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Chunk #6 — Results — Tails of Height

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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
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A total of 134 SNPs from stage 1 were taken forward to stage 2 in up to 4,872 and 4,831 individuals from the upper and lower tails of height, respectively. Of the 95 SNPs that reached P<5×10-8 in the joint meta-analysis of stage 1 and stage 2 (Supplementary Table 6), four novel loci (IGFBP4, H6PD, RSRC1, PPP2R2A) were identified for tails of height (Table 1, Supplementary Fig. 8). The contribution of the four loci to the overall height variability was ≤0.02% (Supplementary Table 7).