(Fig. 4B, R = 0.719, p = 0.008), 10% (Fig. 4C, R = 0.691, p = 0.013), and 14% ethanol (R = 0.591, p = 0.043, data not shown). Although not significant, we observed a trend correlating Lmo3 expression with consumption at 2 additional ethanol concentrations, 3% (R = 0.540, p = 0.07) and 20% (R = 0.527, p = 0.078). To determine if Lmo3 levels were specifically correlated with ethanol consumption or were more generally associated with drinking behavior, we examined the correlation between Lmo3 expression and water consumption, and observed no significant relationship (Fig. 4D, R = 0.353, p = 0.261). Together, these results indicate that lower levels of Lmo3 are associated with decreased voluntary ethanol consumption in mice.
