The recent successes of psychiatric GWAS have unearthed a vast resource of findings when sample sizes became very large (Ripke et al. 2011, for the Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium; Sklar et al. 2011, for the Psychiatric GWAS Consortium Bipolar Disorder Working Group; Cichon et al. 2011, for the MooDS consortium Bipolar Disorder Group; Rietschel et al. 2012, for the MooDS consortium Schizophrenia Group; Cross-Disorder Group of the Psychiatric Genomics Consortium et al. 2013). In fact, it was the need for large samples that encouraged the ENIGMA groups to work together, realizing that otherwise their power to make credible discoveries in genomic scans would be severely limited.
