There have been relatively few studies of genetic variants in relation to EEG parameters, and only one finding that has been replicated to date. There have been reports of associations between variants in the HTR3B gene, which codes for a serotonin receptor, and reduced alpha power, as well as alcohol dependence with comorbid antisocial behavior (Ducci et al., 2009), between the Val158/Met polymorphism of the catechol-O-methyltransferase gene (COMT) and low-frequency power (delta and theta) in schizophrenic patients (Venables et al., 2009) and slower alpha peak frequency in normal controls (Bodenmann et al., 2009), as well as reports of associations between asymmetry in EEG activity and candidate genes (Bismark et al., 2010; Bulgin et al., 2008). The ε4 allele of the apolipoprotein E (APOE) gene, which confers risk for Alzheimer’s dementia (Elias-Sonnenschein, Viechtbauer, Ramakers, Verhey, & Visser, 2011), has been found to be associated with reduced alpha power (Ponomareva, Korovaitseva, & Rogaev, 2008). Most importantly, this association has been observed in healthy young adults (Lee et al., 2012). A similar association has been reported (Ponomareva et al., 2013) between reduced alpha
