Chunk #9 — METHODS — Genetic analysis

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Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities.

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Genomic DNA was isolated using the DNAEasy kit (Qiagen, 69504). Fingerprinting was carried out by the Broad Institute Genomics Platform using the Fluidigm platform according to the manufacturer’s instructions. Whole-genome single nucleotide polymorphism (SNP) genotyping on 733,202 SNPs was carried out by the Broad Genomics Platform using Illumina OmniExpress arrays according to the manufacturer’s instructions.