The sample comprises 1868 BD cases.47 They were over the age of 16 years and of European descent. Individuals who had been in contact with mental health services were recruited if they suffered from a major mood disorder in which clinically significant episodes of elevated mood had occurred, such as bipolar I disorder (71% cases), schizoaffective disorder bipolar type (15% cases), bipolar II disorder (9% cases) and manic disorder (5% cases).