We report genetic variants at 15 loci associated with primary tooth eruption at genome-wide significant levels, including 8 novel variants within or near the following genes: BMP4, CACNB2, CDON, CALU/OPN1SW, AJUBA, DLEU7, TEX14/RAD51C and ADK. We confirm association with six loci previously associated with primary tooth eruption (KCNJ2/KCNJ16, EDA, IGF2BP1, MSRB3, Chr6q21, 2q35) (6). The SNPs from the ADK and 2q35 associations have also been previously associated with secondary tooth eruption (7).
