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coga / coga-kb
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Chunk #1 — METHODS SUMMARY

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Genes mirror geography within Europe.
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PCA was carried out using the smartpca program8,12. Before running PCA, we removed SNPs that showed evidence of high pairwise linkage disequilibrium as well as unique genomic regions (such as large polymorphic inversions) that might obscure genome-wide patterns of population structure. In addition, an initial PCA run was used to remove extreme genetic outliers.