All subjects in these analyses took part in an alcohol challenge using 0.75 ml/kg of ethanol (0.61 gram/kg) incorporating the methods used in the San Diego laboratory (Schuckit and Gold, 1988; Schuckit et al., 1996). Thus, subjects consumed the alcohol as a 20% by volume solution mixed with a carbonated sugar-free beverage using the apparatus described by Mendelson et al. (1984). At baseline (before the drink), and the 15 minutes, 30 minutes, and each half hour thereafter over the 210 minute observation, participants were evaluated for their breath alcohol concentration using the Alko-Intoximeter (St. Louis, Missouri), and filled out the Subjective High Assessment Scale (SHAS), reporting their change from baseline to each measurement point regarding their self-rating of items scored on a 36-point scale (from no alcohol impact to extreme effects) (Judd et al., 1977, Schuckit and Gold, 1988). The SHAS score used here focuses on the 7 items (SHAS 7) with the greatest sensitivity to alcohol effects and the greatest similarity to the items used on the SRE (Eng et al., 2005). These items included ratings of feeling the effects of alcohol overall, feeling drunk, high, clumsy, confused, dizzy, or having difficulty concentrating.
