a small sample of East Asian adolescents adopted into western homes, those with an ALDH2*2 allele were more likely to have consumed alcohol and gotten drunk if they had a sibling that did the same (Irons, McGue, Iacono, & Oetting, 2007), indicative of an environmental interaction with this genotype. There was no effect of adopted parent AUD; however, there was likely insufficient power to detect this effect given the small sample size. The final study investigated the interaction between ADH1B*2 and cultural factors on drinking in Israel among recent Russian Jewish immigrants, Ashkenazi Jews, and Sephardic Jews (Hasin et al., 2002). Overall, individuals with ADH1B*2 allele were less likely to drink heavily. However, the suppressive effects of ADH1B*2 on heavy drinking appeared to be qualitatively weakest among recent Russian immigrants, presumably due to their greater exposure to a heavy drinking culture.
