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Chunk #28 — Methods — Array design objectives

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Smokescreen: a targeted genotyping array for addiction research.
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The array design was driven by the need for a common panel of markers for both hypothesis-driven and genome-wide studies of addiction. This project was funded by the Small Business Innovative Research (SBIR) program with the National Institute on Drug Abuse (NIDA). Specific requirements included capturing prioritized markers identified by NIDA; selecting focused content for a wide variety of research purposes and multiple ethnicities; selecting a platform for accurate and reproducible data across studies, and providing a screening tool for development of risk assessments and personalized approaches to addiction treatment.