We measured gene expression in the hippocampus of these KOs and wildtype using Illumina Sentrix Mouse-6 v1.1 arrays according to the manufacturer's protocols. Array data were normalized using the rank invariant method. Probes were then filtered by expression and only probe sets with above background expression were retained. Differential expression was then assessed by unpaired Student's t-test. Differences are considered significant when a P-value is <0.05.
