Chunk #32 — METHODS — MIXTURE OF REGRESSION MODELS — Non-additive

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A comparison of approaches to account for uncertainty in analysis of imputed genotypes.

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(7)fk(μ,β1,β2,εi)={μ+εi,k=0μ+β1+εi,k=1μ+β2+εi,k=2, where εi ~ (0, σ2). To test the hypothesis H0: β1 =0 β2 =0 vs. H1: β1 ≠ 0, or β2 ≠ 0, we construct a likelihood ratio test.